反应详情

To methylene chloride (200 mL) solution of the compound obtained in Example 28 (8.9 g, 25.7 mmol) was added dropwise 4 mol/L of hydrogen chloride-dioxane (19 mL) at room temperature, and the mixture was allowed to stir for 15 hours. The crystals precipitated were filtered, and washed with diethyl ether, to give the captioned compound (7.2 g, 99%).

1. customThe crystals precipitated
2. filtrationwere filtered
3. washwashed with diethyl ether