Sodium Hydroxide → HCID 131733546, compound

HRID 1746534Notes

Reaction equation

HRID 1746534 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:24]([O:26]C)=[O:25])[CH2:14][C:15]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[NH:17][CH:16]=2)=[O:11])[CH:5]=[CH:6][CH:7]=1.[OH-].[Na+:29]>CO>[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:24]([O-:26])=[O:25])[CH2:14][C:15]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[NH:17][CH:16]=2)=[O:11])[CH:5]=[CH:6][CH:7]=1.[Na+:29]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655441HCID 86655441, compound

Product 1

HCID 131733546HCID 131733546, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 60 were carried out from the compound obtained in Example 6 (4.2 g), 1 mol/L of an aqueous sodium hydroxide solution (17 mL), and methanol (170 mL), to give the captioned compound (3.7 g, 86%) as an amorphous solid product.

Sources & evidence

ORD record
ord-9c12014531584c97b1e9452acd18705d
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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