Sodium Hydroxide → HCID 86655487, compound

HRID 1746535Notes

Reaction equation

HRID 1746535 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:24]([O:26]C)=[O:25])[CH2:14][C:15]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[NH:17][CH:16]=2)=[O:11])=[CH:4][CH:3]=1.[OH-].[Na+:29]>CO>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:24]([O-:26])=[O:25])[CH2:14][C:15]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[NH:17][CH:16]=2)=[O:11])=[CH:6][CH:7]=1.[Na+:29]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655442HCID 86655442, compound

Product 1

HCID 86655487HCID 86655487, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 60 were carried out from the compound obtained in Example 7 (3.0 g), 1 mol/L of an aqueous sodium hydroxide solution (35 mL), and methanol (150 mL), to give the captioned compound (3.0 g, 98%) as crystals.

Sources & evidence

ORD record
ord-986acb3e278940e8bab0ec5e6a0a285c
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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