Sodium Hydroxide → HCID 86655488, compound

HRID 1746536Notes

Reaction equation

HRID 1746536 reaction equation
[C:1]1([CH:7]=[CH:8][C:9]([NH:11][C@H:12]([C:23]([O:25]C)=[O:24])[CH2:13][C:14]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[NH:16][CH:15]=2)=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+:28]>CO>[C:1]1([CH:7]=[CH:8][C:9]([NH:11][C@H:12]([C:23]([O-:25])=[O:24])[CH2:13][C:14]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[NH:16][CH:15]=2)=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Na+:28]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655443HCID 86655443, compound

Product 1

HCID 86655488HCID 86655488, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 60 were carried out from the compound obtained in Example 8 (3.7 g), 1 mol/L of an aqueous sodium hydroxide solution (32 mL), and methanol (150 mL), to give the captioned compound (3.7 g, 98%) as crystals.

Sources & evidence

ORD record
ord-338cb3da1e9d44b4b672fae1c240a91b
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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