Sodium Hydroxide → HCID 86655489, compound

HRID 1746537Notes

Reaction equation

HRID 1746537 reaction equation
[F:1][C:2]([F:30])([F:29])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][C:11]([NH:13][C@H:14]([C:25]([O:27]C)=[O:26])[CH2:15][C:16]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[NH:18][CH:17]=1)=[O:12].[OH-].[Na+:32]>CO>[F:30][C:2]([F:1])([F:29])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][C:11]([NH:13][C@H:14]([C:25]([O-:27])=[O:26])[CH2:15][C:16]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[NH:18][CH:17]=1)=[O:12].[Na+:32]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655490HCID 86655490, compound

Product 1

HCID 86655489HCID 86655489, compoundYield 46%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 60 were carried out from the compound obtained in Example 10 (3.4 g), 1 mol/L of an aqueous sodium hydroxide solution (12 mL), and methanol (120 mL), to give the captioned compound (1.6 g, 46%) as crystals.

Sources & evidence

ORD record
ord-559200e6197843a490350e58c559bf78
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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