Sodium Hydroxide → HCID 86655491, compound

HRID 1746538Notes

Reaction equation

HRID 1746538 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][C:11]([NH:13][C@H:14]([C:25]([O:27]C)=[O:26])[CH2:15][C:16]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[NH:18][CH:17]=1)=[O:12].[OH-].[Na+:30]>CO>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][C:11]([NH:13][C@H:14]([C:25]([O-:27])=[O:26])[CH2:15][C:16]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[NH:18][CH:17]=1)=[O:12].[Na+:30]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655444HCID 86655444, compound

Product 1

HCID 86655491HCID 86655491, compoundYield 55%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 60 were carried out from the compound obtained in Example 11 (5.2 g), 1 mol/L of an aqueous sodium hydroxide solution (42 mL), and methanol (150 mL), to give the captioned compound (2.9 g, 55%) as crystals.

Sources & evidence

ORD record
ord-4627adffc7114a79bff0274162b864c4
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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