Sodium Hydroxide → HCID 67130568, compound

HRID 1746539Notes

Reaction equation

HRID 1746539 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:24]([O:26]C)=[O:25])[CH2:14][C:15]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[NH:17][CH:16]=1)=[O:11].[OH-].[Na+]>CO>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:24]([OH:26])=[O:25])[CH2:14][C:15]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[NH:17][CH:16]=1)=[O:11]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655445HCID 86655445, compound

Product 1

HCID 67130568HCID 67130568, compoundYield 85.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 64 were carried out from the compound obtained in Example 12 (4.5 g), 1 mol/L of an aqueous sodium hydroxide solution (18 mL), and methanol (180 mL), to give the captioned compound (3.7 g, 85%) as crystals.

Sources & evidence

ORD record
ord-70581f71f7a3411692b57b6ff3fdd49e
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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