Sodium Hydroxide → HCID 26794736, compound

HRID 1746546Notes

Reaction equation

HRID 1746546 reaction equation
[O:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([C:12]([NH:14][C@H:15]([C:26]([O:28]C)=[O:27])[CH2:16][C:17]2[C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[NH:19][CH:18]=2)=[O:13])[C:2]1=[O:3].[OH-].[Na+]>CO>[O:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([C:12]([NH:14][C@H:15]([C:26]([OH:28])=[O:27])[CH2:16][C:17]2[C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[NH:19][CH:18]=2)=[O:13])[C:2]1=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 12237954HCID 12237954, compound

Product 1

HCID 26794736HCID 26794736, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 64 were carried out from the compound obtained in Example 19 (2.0 g), 1 mol/L of an aqueous sodium hydroxide solution (7.7 mL), and methanol (80 mL), to give the captioned compound (1.9 g, 99%) as crystals.

Sources & evidence

ORD record
ord-56f7d283eea64282a6c53015a59e3b4d
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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