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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1746560Generated: October 31, 2026

Sodium Hydroxide → N-[3-(2-Fluorophenyl)acryloyl]-O4-Methyl-L-Tyrosine

https://huagongshe.com/reaction/1746560

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 86655467HCID 86655467—
SolventMethanolHCID 887—
ProductN-[3-(2-Fluorophenyl)acryloyl]-O4-Methyl-L-TyrosineHCID 8665550676%

Reaction Steps

The same procedures as in Example 90 were carried out from the compound obtained in Example 38 (5.8 g), 1 mol/L of an aqueous sodium hydroxide solution (24 mL), and methanol (200 mL), to give the captioned compound (4.2 g, 76%) as crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150510B2
Source datasetuspto-grants-2015_10
ORD IDord-ad39b11125a7451180d4cb387cb09de9
Source noteuspto-grants-2015_10