Sodium Hydroxide → HCID 86655508, compound

HRID 1746562Notes

Reaction equation

HRID 1746562 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:23]([O:25]C)=[O:24])[CH2:14][C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[O:11])=[CH:4][CH:3]=1.[OH-].[Na+]>CO>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:23]([OH:25])=[O:24])[CH2:14][C:15]2[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=2)=[O:11])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655469HCID 86655469, compound

Product 1

HCID 86655508HCID 86655508, compoundYield 91.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 90 were carried out from the compound obtained in Example 40 (2.5 g), 1 mol/L of an aqueous sodium hydroxide solution (21 mL), and methanol (150 mL), to give the captioned compound (2.2 g, 90%) as crystals.

Sources & evidence

ORD record
ord-0f7f268502de43cdb67d6f2cbfa120e7
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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