Sodium Hydroxide → HCID 86655509, compound

HRID 1746563Notes

Reaction equation

HRID 1746563 reaction equation
[CH3:1][O:2][C:3]1[CH:25]=[CH:24][C:6]([CH2:7][C@@H:8]([C:20]([O:22]C)=[O:21])[NH:9][C:10](=[O:19])[CH:11]=[CH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:5][CH:4]=1.[OH-].[Na+]>CO>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][C@@H:8]([C:20]([OH:22])=[O:21])[NH:9][C:10](=[O:19])[CH:11]=[CH:12][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)=[CH:24][CH:25]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655470HCID 86655470, compound

Product 1

HCID 86655509HCID 86655509, compoundYield 62%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 90 were carried out from the compound obtained in Example 41 (3.4 g), 1 mol/L of an aqueous sodium hydroxide solution (19 mL), and methanol (150 mL), to give the captioned compound (2.0 g, 62%) as crystals.

Sources & evidence

ORD record
ord-55f9c7983c254d6795e296bb76a48529
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

Loading…