Sodium Hydroxide → HCID 86655512, compound

HRID 1746566Notes

Reaction equation

HRID 1746566 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][C:11]([NH:13][C@H:14]([C:24]([O:26]C)=[O:25])[CH2:15][C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=1)=[O:12].[OH-].[Na+]>CO>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][C:11]([NH:13][C@H:14]([C:24]([OH:26])=[O:25])[CH2:15][C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=1)=[O:12]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 67130883HCID 67130883, compound

Product 1

HCID 86655512HCID 86655512, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 90 were carried out from the compound obtained in Example 44 (1.6 g), 1 mol/L of an aqueous sodium hydroxide solution (13 mL), and methanol (150 mL), to give the captioned compound (1.2 g, 75%) as crystals.

Sources & evidence

ORD record
ord-ae87c95dd71041c2a38f121b9a87ca8f
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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