Sodium Hydroxide → HCID 86655513, compound

HRID 1746567Notes

Reaction equation

HRID 1746567 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:23]([O:25]C)=[O:24])[CH2:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)=[O:11].[OH-].[Na+]>CO>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:23]([OH:25])=[O:24])[CH2:14][C:15]1[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=1)=[O:11]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655473HCID 86655473, compound

Product 1

HCID 86655513HCID 86655513, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 64 were carried out from the compound obtained in Example 45 (2.9 g), 1 mol/L of an aqueous sodium hydroxide solution (12 mL), and methanol (120 mL), to give the captioned compound (2.4 g, 79%) as crystals.

Sources & evidence

ORD record
ord-83dd33cdb9d3433cb0a0c060224dcc27
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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