HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → N-[3-(2,6-Difluorophenyl)acryloyl]-O4-Methyl-L-Tyrosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl N-[3-(2,6-Difluorophenyl)acryloyl]-O4-Methyl-L-Tyrosinate | HCID 86655474 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-[3-(2,6-Difluorophenyl)acryloyl]-O4-Methyl-L-Tyrosine | HCID 86655514 | 97% |
Reaction Steps
The same procedures as in Example 64 were carried out from the compound obtained in Example 46 (3.0 g), 1 mol/L of an aqueous sodium hydroxide solution (12 mL), and methanol (120 mL), to give the captioned compound (2.8 g, 95%) as crystals,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150510B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-b88d26df1dc942dea74d67507e4cf1c2 |
| Source note | uspto-grants-2015_10 |