Sodium Hydroxide → HCID 86655517, compound

HRID 1746572Notes

Reaction equation

HRID 1746572 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[C:10]([NH:12][C@H:13]([C:23]([O:25]C)=[O:24])[CH2:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)=[O:11].[OH-].[Na+]>CO>[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[C:10]([NH:12][C@H:13]([C:23]([OH:25])=[O:24])[CH2:14][C:15]1[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=1)=[O:11]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655478HCID 86655478, compound

Product 1

HCID 86655517HCID 86655517, compoundYield 79.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 64 were carried out from the compound obtained in Example 51 (3.4 g), 1 mol/L of an aqueous sodium hydroxide solution (15 mL), and methanol (150 mL), to give the captioned compound (2.6 g, 78%) as crystals.

Sources & evidence

ORD record
ord-e345697dffe4448f878b87572f4bf851
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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