Sodium Hydroxide → HCID 86655518, compound

HRID 1746573Notes

Reaction equation

HRID 1746573 reaction equation
[O:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([C:12]([NH:14][C@H:15]([C:25]([O:27]C)=[O:26])[CH2:16][C:17]2[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=2)=[O:13])[C:2]1=[O:3].[OH-].[Na+]>CO>[O:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([C:12]([NH:14][C@H:15]([C:25]([OH:27])=[O:26])[CH2:16][C:17]2[CH:18]=[CH:19][C:20]([O:23][CH3:24])=[CH:21][CH:22]=2)=[O:13])[C:2]1=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655479HCID 86655479, compound

Product 1

HCID 86655518HCID 86655518, compoundYield 80.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 90 were carried out from the compound obtained in Example 52 (2.7 g), 1 mol/L of an aqueous sodium hydroxide solution (11 mL), and methanol (110 mL), to give the captioned compound (2.1 g, 80%) as crystals.

Sources & evidence

ORD record
ord-314694f5e277453caadd61db791f4ce6
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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