Sodium Hydroxide → HCID 61152278, compound

HRID 1746576Notes

Reaction equation

HRID 1746576 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:18]([O:20]C)=[O:19])[CH2:14][CH2:15][S:16][CH3:17])=[O:11].[OH-].[Na+]>CO>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:18]([OH:20])=[O:19])[CH2:14][CH2:15][S:16][CH3:17])=[O:11]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 67311344HCID 67311344, compound

Product 1

HCID 61152278HCID 61152278, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 64 were carried out from the compound obtained in Example 55 (3.7 g), 1 mol/L of an aqueous sodium hydroxide solution (18 mL), and methanol (180 mL), to give the captioned compound (3.0 g, 85%) as crystals.

Sources & evidence

ORD record
ord-34b46f61e3c640f2b0ffb12580454ee6
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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