Sodium Hydroxide → HCID 86655521, compound

HRID 1746579Notes

Reaction equation

HRID 1746579 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:26]([O:28]C)=[O:27])[CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])=[O:11].[OH-].[Na+]>CO>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:26]([OH:28])=[O:27])[CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19]([O:21][C:22]([CH3:23])([CH3:25])[CH3:24])=[O:20])=[O:11]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86655522HCID 86655522, compound

Product 1

HCID 86655521HCID 86655521, compoundYield 98.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 111 were carried out from the compound obtained in Example 58 (4.0 g), 1 mol/L of an aqueous sodium hydroxide solution (16 mL), and methanol (160 mL), to give the captioned compound (3.8 g, 98%) as an oily product.

Sources & evidence

ORD record
ord-7a30cec092fe4ac09b460c53b67e7246
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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