Sodium Hydroxide → HCID 178421682, compound

HRID 1746581Notes

Reaction equation

HRID 1746581 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:38]([O:40]C)=[O:39])[CH2:14][CH2:15][CH2:16][NH:17][C:18](=[NH:37])[NH:19][S:20]([C:23]1[CH:33]([CH3:34])[CH:27]2[CH2:28][C:29]([CH3:32])([CH3:31])[O:30][C:26]2=[C:25]([CH3:35])[C:24]=1[CH3:36])(=[O:22])=[O:21])=[O:11].[OH-].[Na+]>CO>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:38]([OH:40])=[O:39])[CH2:14][CH2:15][CH2:16][NH:17][C:18](=[NH:37])[NH:19][S:20]([C:23]1[CH:33]([CH3:34])[CH:27]2[CH2:28][C:29]([CH3:32])([CH3:31])[O:30][C:26]2=[C:25]([CH3:35])[C:24]=1[CH3:36])(=[O:22])=[O:21])=[O:11]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178501464HCID 178501464, compound

Product 1

HCID 178421682HCID 178421682, compoundYield 91%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 111 were carried out from the compound obtained in Example 59 (3.2 g), 1 mol/L of an aqueous sodium hydroxide solution (8.0 mL), and methanol (80 mL), to give the captioned compound (2.8 g, 91%) as an oily product.

Sources & evidence

ORD record
ord-32c39d04a94f484c98ac2c51c93cc992
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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