HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 86655527, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 1-Methyl-L-tryptophan | HCID 676159 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86655527 | HCID 86655527 | 68.9% |
Reaction Steps
The same procedures as in Example 121 were carried out from 1-methyl-L-tryptophan (2.0 g), sodium hydrogencarbonate (0.8 g), 2,5-dioxopyrrolidin-1-yl 3-phenyl acrylate (2.3 g), water (60 mL), and dioxane (140 mL), to give the captioned compound (1.1 g, 33%) as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150510B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-58ebbc66b79f45c6ae5a7e5429b98297 |
| Source note | uspto-grants-2015_10 |