HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 61145156, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | L-Glutamine | HCID 5961 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 86655531 | HCID 86655531 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 61145156 | HCID 61145156 | 58% |
Reaction Steps
The same procedures as in Example 129 were carried out from L-glutamine (2.0 g), 2,5-dioxopyrrolidin-1-yl 3-(2-fluorophenyl)acrylate (3.6 g), sodium hydrogencarbonate (1.2 g), water (60 mL), and dioxane (160 mL), to give the captioned compound (2.3 g, 58%) as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150510B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-306e394dd206410082c91054344dc91c |
| Source note | uspto-grants-2015_10 |