Sodium Hydroxide → HCID 86655533, compound

HRID 1746604Notes

Reaction equation

HRID 1746604 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:27]([O:29]C)=[O:28])[CH2:14][C:15]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[N:17]([CH:24]([CH3:26])[CH3:25])[CH:16]=1)=[O:11].[OH-].[Na+]>CO>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([NH:12][C@H:13]([C:27]([OH:29])=[O:28])[CH2:14][C:15]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[N:17]([CH:24]([CH3:26])[CH3:25])[CH:16]=1)=[O:11]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 67130477HCID 67130477, compound

Product 1

HCID 86655533HCID 86655533, compoundYield 71%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 149 were carried out from the compound obtained in Example 147 (0.98 g), 1 mol/L of an aqueous sodium hydroxide solution (3.6 mL), and methanol (40 mL), to give the captioned compound (0.67 g, 71%) as crystals.

Sources & evidence

ORD record
ord-b51abae8237841f0b60abbe5c3379277
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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