Sodium Hydroxide → HCID 29069660, compound

HRID 1746621Notes

Reaction equation

HRID 1746621 reaction equation
[CH3:1][C:2]([CH3:22])=[CH:3][C:4]([NH:6][C@H:7]([C:18]([O:20]C)=[O:19])[CH2:8][C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[NH:11][CH:10]=1)=[O:5].[OH-].[Na+]>CO>[CH3:1][C:2]([CH3:22])=[CH:3][C:4]([NH:6][C@H:7]([C:18]([OH:20])=[O:19])[CH2:8][C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[NH:11][CH:10]=1)=[O:5]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 67130467HCID 67130467, compound

Product 1

HCID 29069660HCID 29069660, compoundYield 79.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 171 were carried out from the compound obtained in Example 162 (2.5 g), 1 mol/L of an aqueous sodium hydroxide solution (13 mL), and methanol (130 mL), to give the captioned compound (1.9 g, 78%) as an amorphous solid product.

Sources & evidence

ORD record
ord-586da4eb4a74479193780901ce93c0b1
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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