Sodium Hydroxide → HCID 67130589, compound

HRID 1746623Notes

Reaction equation

HRID 1746623 reaction equation
[CH3:1][C:2](=[CH:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:3]([NH:5][C@H:6]([C:17]([O:19]C)=[O:18])[CH2:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:10][CH:9]=1)=[O:4].[OH-].[Na+]>CO>[CH3:1][C:2](=[CH:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:3]([NH:5][C@H:6]([C:17]([OH:19])=[O:18])[CH2:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:10][CH:9]=1)=[O:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 67130595HCID 67130595, compound

Product 1

HCID 67130589HCID 67130589, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The same procedures as in Example 149 were carried out from the compound obtained in Example 165 (4.0 g), 1 mol/L of an aqueous sodium hydroxide solution (17 mL), and methanol (170 mL), to give the captioned compound (3.4 g, 89%) as crystals.

Sources & evidence

ORD record
ord-e54154e2d30f4d5b949089804c633246
Source dataset
uspto-grants-2015_10
Patent number
US09150510B2

Reaction notes

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