Sulfanilamide → HCID 25182755, compound

HRID 1746702Notes

Reaction equation

HRID 1746702 reaction equation
[CH:1]1([NH:7][C:8]2[N:13]=[CH:12][N:11]=[C:10]([C:14]([OH:16])=O)[CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[S:17]([NH2:27])(=[O:26])([C:19]1[CH:24]=[CH:23][C:22]([NH2:25])=[CH:21][CH:20]=1)=[O:18]>CO>[NH2:27][S:17]([C:19]1[CH:20]=[CH:21][C:22]([NH:25][C:14]([C:10]2[CH:9]=[C:8]([NH:7][CH:1]3[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]3)[N:13]=[CH:12][N:11]=2)=[O:16])=[CH:23][CH:24]=1)(=[O:18])=[O:26]

Participants

4

Reactant 2

HCID 5333SulfanilamideHCID 594470756-(Cyclohexylamino)pyrimidine-4-carboxylic acid2×

Product 1

HCID 25182755HCID 25182755, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Following the general method as outlined in Example 1, starting from 6-(cyclohexylamino)pyrimidine-4-carboxylic acid (Intermediate 4) and sulfanilamide (Acros), the title compound was obtained as a white solid after trituration in methanol.

Sources & evidence

ORD record
ord-1648301dbf5a4d50bc88ee047e1076c0
Source dataset
uspto-grants-2015_10
Patent number
US09150519B2

Reaction notes

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