Dipropylamine → HCID 46880801, compound
Reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([C:8]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][C:12]=2C)=[O:9])[CH:3]=1.[CH2:19]([NH:22][CH2:23][CH2:24][CH3:25])[CH2:20][CH3:21]>>[CH2:19]([N:22]([CH2:23][CH2:24][CH3:25])[C:2]1[N:7]=[CH:6][N:5]=[C:4]([C:8]([NH:10][C:11]2[CH:12]=[CH:13][C:14]([OH:17])=[CH:15][CH:16]=2)=[O:9])[CH:3]=1)[CH2:20][CH3:21]Participants
3
Procedure
Following the general method as outlined in Example 20, starting from 6-chloro-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide (Intermediate 7) and dipropylamine (Aldrich), the title compound was obtained as a brown solid.
Sources & evidence
- ORD record
- ord-56d69b7417f74854aa2aae503b378d82
- Source dataset
- uspto-grants-2015_10
- Patent number
- US09150519B2
Reaction notes
Loading…