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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1746731Generated: November 1, 2026

4-Aminophenethyl alcohol → 6-(cyclohexylamino)-N-(4-(2-hydroxyethyl)phenyl)pyrimidine-4-carboxamide

https://huagongshe.com/reaction/1746731

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Aminophenethyl alcoholHCID 66904—
Reactant6-(Cyclohexylamino)pyrimidine-4-carboxylic acidHCID 59447075—
SolventAcetonitrileHCID 6342—
Product6-(cyclohexylamino)-N-(4-(2-hydroxyethyl)phenyl)pyrimidine-4-carboxamideHCID 25182780—

Reaction Steps

Following the general method as outlined in Example 1, starting from 6-(cyclohexylamino)pyrimidine-4-carboxylic acid (Intermediate 4) and 2-(4-aminophenyl)ethanol (Fluka), the title compound was obtained as a white solid after trituration in acetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150519B2
Source datasetuspto-grants-2015_10
ORD IDord-ff913bb2021f4a59b80964d3849a6162
Source noteuspto-grants-2015_10