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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1746743Generated: October 25, 2026

N-(2-methoxyethyl)cyclohexanamine → 6-[cyclohexyl(2-methoxyethyl)amino]-N-1H-indazol-5-ylpyrimidine-4-carboxamide

https://huagongshe.com/reaction/1746743

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-methoxyethyl)cyclohexanamineHCID 12687399—
Reactant6-chloro-N-1H-indazol-5-ylpyrimidine-4-carboxamideHCID 59446880—
Product6-[cyclohexyl(2-methoxyethyl)amino]-N-1H-indazol-5-ylpyrimidine-4-carboxamideHCID 25182916—

Reaction Steps

Following the general method as outlined in Example 20, starting from 6-chloro-pyrimidine-4-carboxylic acid (1H-indazol-5-yl)-amide (Intermediate 16) and cyclohexyl-(2-methoxy-ethyl)-amine (Intermediate 26), the title compound was obtained as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150519B2
Source datasetuspto-grants-2015_10
ORD IDord-3c2b29b45b1148d6bc5b370349c5efe9
Source noteuspto-grants-2015_10