Dipropylamine → HCID 25182910, compound

HRID 1746745Notes

Reaction equation

HRID 1746745 reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([C:8]([NH:10][C:11]2[CH:12]=[C:13]3[C:17](=[CH:18][CH:19]=2)[NH:16][N:15]=[CH:14]3)=[O:9])[CH:3]=1.[CH2:20]([NH:23][CH2:24][CH2:25][CH3:26])[CH2:21][CH3:22]>>[CH2:20]([N:23]([CH2:24][CH2:25][CH3:26])[C:2]1[N:7]=[CH:6][N:5]=[C:4]([C:8]([NH:10][C:11]2[CH:12]=[C:13]3[C:17](=[CH:18][CH:19]=2)[NH:16][N:15]=[CH:14]3)=[O:9])[CH:3]=1)[CH2:21][CH3:22]

Participants

3

Reactant 2

HCID 8902DipropylamineHCID 594468806-chloro-N-1H-indazol-5-ylpyrimidine-4-carboxamide2×

Product 1

HCID 25182910HCID 25182910, compound

Procedure

Following the general method as outlined in Example 20, starting from 6-chloro-pyrimidine-4-carboxylic acid (1h-indazol-5-yl)-amide (Intermediate 16) and dipropylamine (Aldrich), the title compound was obtained as a white solid.

Sources & evidence

ORD record
ord-59214b4641e14240872213bf36f8e91f
Source dataset
uspto-grants-2015_10
Patent number
US09150519B2

Reaction notes

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