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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1746754Generated: October 30, 2026

Trifluoroacetic acid → HCID 68482016, compound

https://huagongshe.com/reaction/1746754

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59447060HCID 59447060—
SolventDichloromethaneHCID 6344—
ProductHCID 68482016HCID 6848201677%

Reaction Steps

A solution of tert-butyl N-{4-[({6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]benzyl}glycinate (Example 73; 60 mg; 0.12 mmol) in DCM (5 ml) was treated with trifluoroacetic acid (200 μl; 2.61 mmol) and the reaction mixture was stirred at room temperature for 24 hours. The solvents were removed to give the title compound as a yellow oil in 77% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150519B2
Source datasetuspto-grants-2015_10
ORD IDord-ca36c48bc14c4383ac309ba923ef6ae3
Source noteuspto-grants-2015_10