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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1746757Generated: October 31, 2026

3-azetidinecarboxylic Acid → HCID 25182928, compound

https://huagongshe.com/reaction/1746757

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-azetidinecarboxylic AcidHCID 93192—
Reactant6-[cyclohexyl(cyclopropylmethyl)amino]-N-(4-formylphenyl)pyrimidine-4-carboxamideHCID 59446846—
ProductHCID 25182928HCID 25182928—

Reaction Steps

Following the general method as outlined in Example 73, starting from 6-[cyclohexyl(cyclopropylmethyl)amino]-N-(4-formylphenyl)pyrimidine-4-carboxamide (Intermediate 24) and azetidine-3-carboxylic acid (Apollo), the title compound was obtained as a yellow solid after precipitation from DCM/MeOH.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150519B2
Source datasetuspto-grants-2015_10
ORD IDord-15b194aca98649b5a71b6982384ff8cd
Source noteuspto-grants-2015_10