HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Amino-3-methylphenyl)methanol → HCID 25182929, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Amino-3-methylphenyl)methanol | HCID 1514189 | — |
| Reactant | 6-[(Cyclopropylmethyl)(propyl)amino]pyrimidine-4-carboxylic acid | HCID 59447000 | — |
| Product | HCID 25182929 | HCID 25182929 | — |
Reaction Steps
Following the general method as outlined in Example 1, starting from 6-[(cyclopropylmethyl)(propyl)amino]pyrimidine-4-carboxylic acid (Intermediate 21) and (4-amino-3-methylphenyl)methanol (Intermediate 28), the title compound was obtained as a white solid after purification by column chromatography (silica) eluting with cyclohexane containing increasing amounts of EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150519B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-87c49eb8ae6840c5b5a6c6ddf48d158d |
| Source note | uspto-grants-2015_10 |