HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 3-Bromo-4-(trifluoromethoxy)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | p-(Trifluoromethoxy)benzaldehyde | HCID 69573 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 3-Bromo-4-(trifluoromethoxy)benzaldehyde | HCID 13150416 | — |
Reaction Steps
To 68 g (0.36 mol) of 4-Trifluoromethoxybenzaldehyde dissolved in a mixture of 100 ml CH2Cl2, 100 ml TFA and 50 ml conc. H2SO4 are added within 7 h 130 g (0.72 mol) N-bromo-succinimide in small portions under stirring at room temperature (r.t.). The reaction mixture is stirred for 2 days at r.t.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150544B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-8d229bb203ff4a03a8e404e1a86c7686 |
| Source note | uspto-grants-2015_10 |