HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-2-hydroxy-4-phenylbutanamide → HCID 89855374, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-2-hydroxy-4-phenylbutanamide | HCID 13882355 | — |
| Reactant | HCID 117926092 | HCID 117926092 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 89855374 | HCID 89855374 | 100.1% |
Reaction Steps
Coupling of sodium 2-(3-((4,4-difluoropiperidin-1-yl)methyl)-1H-pyrazol-1-yl)nicotinate (310 mg, 0.900 mmol) and 3-amino-2-hydroxy-4-phenylbutanamide (227 mg, 1.171 mmol) in N,N-dimethylformamide (20 mL) according to example 1.3 and work-up gave 449 mg of the title compound; ESI-MS [M+H]+: 499.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150545B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-08c5f5a0daab40d6a0ab8996a5d0667d |
| Source note | uspto-grants-2015_10 |