HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 117925846, compound → HCID 71768810, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 117925846 | HCID 117925846 | — |
| Solvent | Acetonitrile--water (1/1) | HCID 18373917 | — |
| Product | HCID 71768810 | HCID 71768810 | 49.5% |
Reaction Steps
Oxidation of tert-butyl 2-(3-(4-amino-3-hydroxy-4-oxo-1-phenylbutan-2-ylcarbamoyl)pyridin-2-yl)-4,5-dihydro-2H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate (170 mg, 0.327 mmol) as described in example 1.4 and purification by chromatography over Chromabond RP-C18 (eluent: water/acetonitrile) gave 84 mg of an amorphous solid; ESI-MS [M+H]+: 519.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150545B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-8b5307c818474d5ebc45ff0e170f9468 |
| Source note | uspto-grants-2015_10 |