HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-2-hydroxy-4-phenylbutanamide → HCID 89852571, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-2-hydroxy-4-phenylbutanamide | HCID 13882355 | — |
| Reactant | HCID 89852240 | HCID 89852240 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 89852571 | HCID 89852571 | 47% |
Reaction Steps
Coupling of 2-(3-(1-methylpiperidin-4-yl)-1H-pyrazol-1-yl)nicotinic acid (360 mg, 1.257 mmol) and 3-amino-2-hydroxy-4-phenylbutanamide (293 mg, 1.509 mmol) in dichloromethane (50 mL) according to the procedure described for example 1.3 and recrystallization from ethylacetate afforded 273 mg of the title compound; ESI-MS [M+H]+: 463.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150545B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-43f281b7ceca422f9ee957ff7d9fe8b3 |
| Source note | uspto-grants-2015_10 |