HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 17471Generated: October 26, 2026
Triethylamine → HCID 68587085, compound
https://huagongshe.com/reaction/17471
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | (3S)-(-)-3-(Dimethylamino)pyrrolidine | HCID 7019156 | — |
| Reactant | 7-Fluoro-5-methyl-6-phenyl-2-(1,3-thiazol-2-yl)-1,3-benzoxazole-4-carbonitrile | HCID 68584428 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 68587085 | HCID 68587085 | — |
Reaction Steps
(3S)-3-(Dimethylamino)pyrrolidine (48.4 μl, 0.382 mmol) and triethylamine (53.2 μl, 0.382 mmol) were added to a dimethyl sulfoxide (1 ml) solution of 7-fluoro-5-methyl-6-phenyl-2-(1,3-thiazol-2-yl)-1,3-benzoxazole-4-carbonitrile (I-186) (64.0 mg, 0.191 mmol), followed by stirring in an oil bath at 100° C. for 3 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07737166B2 |
|---|
| Source dataset | uspto-grants-2010_06 |
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| ORD ID | ord-a0d94b4133d84905b272079515fd49e7 |
|---|
| Source note | uspto-grants-2010_06 |
|---|
