HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-methoxydihydro-2H-pyran-4(3H)-one → benzyl 4-((3aS,5S,6aR)-5-(((3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl)amino)hexahydro-2H-cyclopenta[b]furan-3a-carbonyl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-methoxydihydro-2H-pyran-4(3H)-one | HCID 11320949 | — |
| Reactant | benzyl 4-((3aS,5S,6aR)-5-aminohexahydro-2H-cyclopenta[b]furan-3a-carbonyl)piperazine-1-carboxylate | HCID 86708145 | — |
| Product | benzyl 4-((3aS,5S,6aR)-5-(((3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl)amino)hexahydro-2H-cyclopenta[b]furan-3a-carbonyl)piperazine-1-carboxylate | HCID 86708144 | — |
Reaction Steps
The product of Step H was prepared from the reaction of the product of Step G and (R)-3-methoxydihydro-2H-pyran-4(3H)-one (Intermediate 1) following the procedure described in Example 1, Step H. Calculated for C26H37N3O6: 488.3 (M+1). found: 488.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150532B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-a8b4fba42ca942ee8455118125b750d5 |
| Source note | uspto-grants-2015_10 |