Hydrazine hydrate (1:1) → 3-Nitrobenzohydrazide

Participants

Reaction Steps

Methyl 3-nitrobenzoate (940.70 mg; 5.19 mmol; 1.00 eq.) is dissolved in EtOH (24.00 ml). Hydrazine hydrate (4.04 ml; 83.09 mmol; 16.00 eq.) is added and the mixture is stirred 1 hour at RT. It is stirred at 60° C. for 6 hours and RT overnight. The precipitate formed is filtrated and dried under vacuo, affording 3-nitrobenzohydrazide as white-off solid (815.90 mg; 86.73%). 1H NMR (DMSO-d6) δ: 4.62 (s, 2H), 7.76 (m, 1H), 8.24 (m, 1H), 8.36 (m, 1H), 8.63 (s, 1H), 10.15 (s, 1H).

Provenance & Evidence