Benzene, 1,3-diiodo- → HCID 68742521, compound

HRID 1747237Notes

Reaction equation

HRID 1747237 reaction equation
I[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([I:8])[CH:3]=1.S1(=O)(=O)[N:13]2[CH2:14][CH2:15][CH2:16][CH2:17][C@H:12]2[CH2:11]O1>>[I:8][C:4]1[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=1)[CH2:11][C@@H:12]1[CH2:17][CH2:16][CH2:15][CH2:14][NH:13]1

Participants

3

Reactant 2

HCID 12270Benzene, 1,3-diiodo-HCID 18346021HCID 18346021, compound

Product 1

HCID 68742521HCID 68742521, compound

Procedure

(S)-2-(3-Iodo-benzyl)-piperidine was prepared from 1,3-diiodobenzene and (S)-hexahydro-[1,2,3]oxathiazolo[3,4-a]pyridine 1,1-dioxide in analogy to the procedure described for Example 4 in U.S. Pat. No. 5,130,432. LC-MS B: tR=0.54 min; [M+H]+=302.07.

Sources & evidence

ORD record
ord-4a42b66209ff44bbbc7f3b96ad9df937
Source dataset
uspto-grants-2015_10
Patent number
US09150566B2

Reaction notes

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