Isobutane → HCID 89560031, compound

HRID 1747238Notes

Reaction equation

HRID 1747238 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][C@H:9]1[CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17](I)[CH:16]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH:22]1[CH:26]=[CH:25][N:24]=[N:23]1.C(C)(C)C>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][C@H:9]1[CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N:23]2[N:24]=[CH:25][CH:26]=[N:22]2)[CH:16]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 6360IsobutaneHCID 89559896HCID 89559896, compoundHCID 178418936HCID 178418936, compound

Product 1

HCID 89560031HCID 89560031, compound

Procedure

(S)-2-(3-[1,2,3]Triazol-2-yl-benzyl)-piperidine-1-carboxylic acid tert-butyl ester was prepared from (S)-2-(3-iodo-benzyl)-piperidine-1-carboxylic acid tert-butyl ester and 1H-1,2,3-triazole in analogy to the procedure described for A-13. LC-MS C: tR=1.05 min; [M+H-tBu]+=287.08.

Sources & evidence

ORD record
ord-cb2b0851d4b24f7681cac81706f13fa9
Source dataset
uspto-grants-2015_10
Patent number
US09150566B2

Reaction notes

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