5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid → HCID 89560395, compound

HRID 1747240Notes

Reaction equation

HRID 1747240 reaction equation
Cl.[N:2]1[N:3]([C:7]2[CH:8]=[C:9]([CH:17]=[CH:18][CH:19]=2)[CH2:10][C@@H:11]2[CH2:16][CH2:15][CH2:14][CH2:13][NH:12]2)[N:4]=[CH:5][CH:6]=1.[CH3:20][C:21]1[CH:22]=[CH:23][C:24]([N:30]2[N:34]=[CH:33][CH:32]=[N:31]2)=[C:25]([CH:29]=1)[C:26](O)=[O:27]>>[CH3:20][C:21]1[CH:22]=[CH:23][C:24]([N:30]2[N:34]=[CH:33][CH:32]=[N:31]2)=[C:25]([C:26]([N:12]2[CH2:13][CH2:14][CH2:15][CH2:16][C@H:11]2[CH2:10][C:9]2[CH:17]=[CH:18][CH:19]=[C:7]([N:3]3[N:4]=[CH:5][CH:6]=[N:2]3)[CH:8]=2)=[O:27])[CH:29]=1

Participants

3

Reactant 2

HCID 532601655-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acidHCID 89560036HCID 89560036, compound

Product 1

HCID 89560395HCID 89560395, compound

Procedure

The title compound was prepared from (S)-2-(3-[1,2,3]triazol-2-yl-benzyl)-piperidine hydrochloride and 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid E-3 following the procedure described for B-28. LC-MS D: tR=0.94 min; [M+H]+=427.92.

Sources & evidence

ORD record
ord-914c0464d62f4c368947e917e16ebd6f
Source dataset
uspto-grants-2015_10
Patent number
US09150566B2

Reaction notes

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