Methyl 2-((2-nitrophenyl)amino)benzoate → Methyl 2-(2-aminoanilino)benzoate

Participants

Reaction Steps

2-(2-Nitro-phenylamino)-benzoic acid methyl ester (200 mg, 0.74 mmol) is suspended in EtOAc (5.0 mL)) and 10% Pd/C wet (78 mg, 0.073 mmol) is added into it. A H2 balloon is attached to the reaction flask and the reaction mixture is stirred under H2 for 20 hrs. Then the Pd/C is filtered and the filtrated is concentrated to give 165 mg (93%) of 2-(2-Amino-phenylamino)-benzoic acid methyl ester.

Provenance & Evidence