HCID 59497653, compound → HCID 59497441, compound

Participants

Reaction Steps

To a solution of 3-[2-Oxo-3-(3,3,5-tribromo-1-methyl-2-oxo-2,3-dihydro-1H-indol-7-ylmethyl)-2,3-dihydro-benzimidazol-1-yl]-hexanoic acid (20 mg, 0.031 mmol) in acetic acid (5 mL) was added Zinc powder (10 mg, 0.16 mmol) at room temperature. The mixture was stirred at the same temperature for 30 minutes. The mixture was filtered and the filtrate was concentrated. The residue was cool in an ice bath and water was added. The solid that precipitate out from the solution was collected by filtration and was washed with water. The white solid was dried in an oven and was confirmed to be the desirable product (8.9 mg, 59%). LCMS (ESMS): m/z 488.12 (M+H+).

Provenance & Evidence