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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 174746Generated: October 30, 2026

2-chloro-N4-(3,4-difluoromethylenedioxyphenyl)-5-fluoro-4-pyrimidineamine → (+/-)-N2-(2,3-dihydro-2-methoxycarbonylbenzofuran-5-yl)-N4-(3,4-difluoromethylenedioxyphenyl)-5-fluoro-2,4-pyrimidinediamine

https://huagongshe.com/reaction/174746

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-chloro-N4-(3,4-difluoromethylenedioxyphenyl)-5-fluoro-4-pyrimidineamineHCID 22060214—
ReactantMethyl 5-amino-2,3-dihydrobenzofuran-2-carboxylateHCID 22060823—
Product(+/-)-N2-(2,3-dihydro-2-methoxycarbonylbenzofuran-5-yl)-N4-(3,4-difluoromethylenedioxyphenyl)-5-fluoro-2,4-pyrimidinediamineHCID 22060965—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-585a4d079f5a4e5b871263175bd06abe
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)