Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 5-Amino-4,6-dichloropyrimidine | HCID 79434 | — |
| Product | 4,5-Pyrimidinediamine, 6-chloro- | HCID 78010 | — |
Reaction Steps
A suspension of 5-Amino-4,6-dichloropyrimidine (3 g, 0.02 mol) in ammonia (25 mL, 7N/MeOH, 0.175 mole) was heated at 118° C. overnight (under pressure). The reaction was cooled to 23° C., filtered and washed with ethanol to obtain 1.92 g (70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09150525B2 |
|---|
| Source dataset | uspto-grants-2015_10 |
|---|
| ORD ID | ord-8183950ac2df4ba4bf626bdbf396f28a |
|---|
| Source note | uspto-grants-2015_10 |
|---|
