Acetic Acid → Tert-butyl (6-(7-(2-fluoro-4-ureidophenoxy)thieno[3,2-b]pyridin-2-yl)pyridin-3-yl)methyl(2-methoxyethyl)carbamate

HRID 174772Notes

Reaction equation

HRID 174772 reaction equation
[C:42]([OH:43])(=[O:44])[CH3:45].[NH2:1][c:2]1[cH:3][c:4]([F:37])[c:5]([O:6][c:7]2[c:8]3[c:9]([n:10][cH:11][cH:12]2)[cH:13][c:14](-[c:16]2[cH:17][cH:18][c:19]([CH2:22][N:23]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:31][CH2:32][O:33][CH3:34])[cH:20][n:21]2)[s:15]3)[cH:35][cH:36]1.[Na:38][O:39][C:40]#[N:41].[OH2:46]>>[NH:1]([c:2]1[cH:3][c:4]([F:37])[c:5]([O:6][c:7]2[c:8]3[c:9]([n:10][cH:11][cH:12]2)[cH:13][c:14](-[c:16]2[cH:17][cH:18][c:19]([CH2:22][N:23]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:31][CH2:32][O:33][CH3:34])[cH:20][n:21]2)[s:15]3)[cH:35][cH:36]1)[C:40](=[O:39])[NH2:41]

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 962WaterHCID 579194724-[[2-[5-[[Boc(2-methoxyethyl)amino]methyl]-2-pyridyl]-7-thieno[3,2-b]pyridyl]oxy]-3-fluoroanilineHCID 178418852HCID 178418852, compound

Product 1

HCID 57919596Tert-butyl (6-(7-(2-fluoro-4-ureidophenoxy)thieno[3,2-b]pyridin-2-yl)pyridin-3-yl)methyl(2-methoxyethyl)carbamate

Sources & evidence

ORD record
ord-009cb90fb6134f00842b7ec9237e1f9a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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