Water → HCID 89586330, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 1-(3-bromofuran-2-yl)-2-{[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]hydrazono}butane-1,3-dione (5.3 g) and potassium carbonate (3.5 g) in DMF (40 mL) was stirred at 90° C. for 4 hr. The reaction mixture was poured into water, and the mixture was extracted with ethyl acetate. The extract was washed with water and saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. The residue was suspended in diisopropylether, and the precipitate was collected by filtration to give the title compound (2.56 g).

Provenance & Evidence