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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 174779Generated: October 25, 2026

Dimethylformamide → 4-[2-Chloro-4-(1-ethyl-propylamino)-pyrimidin-5-yl]-but-3-yn-2-ol

https://huagongshe.com/reaction/174779

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant3-Butyn-2-olHCID 16239—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant5-bromo-2-chloro-N-(pentan-3-yl)pyrimidin-4-amineHCID 58015891—
Product4-[2-Chloro-4-(1-ethyl-propylamino)-pyrimidin-5-yl]-but-3-yn-2-olHCID 86637349—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-f195a164ec1f4678b2df3012717bc3e5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)