HCID 89586077, compound → HCID 68014851, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 1-(1-benzylpiperidin-4-yl)-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one (2.6 g) in methanol (30 mL) was added palladium hydroxide on carbon (10% wet, 0.30 g). The reaction mixture was stirred at 50° C. for 4 hr under a hydrogen atmosphere. The reaction mixture was filtered through celite, the filtrate was concentrated under reduced pressure, and the obtained crystals were recrystallized from methanol/ethyl acetate to give the title compound (0.75 g).

Provenance & Evidence